Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 5/20 | 0.47 |
| ▸ | HRH1 | P35367 | 5/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524401 | 1.00 | HRH3 (0.54) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL14649680 | 1.00 | HRH3 (0.54) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL14649679 | 0.95 | HRH3 (0.50) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL20083485 | 0.94 | ESR2 (0.57) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL30150 | 0.94 | ESR2 (0.57) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL16488063 | 0.94 | ESR2 (0.57) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL10766113 | 0.89 | ESR2 (0.52) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL10909714 | 0.89 | ESR2 (0.52) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL9338854 | 0.87 | HRH3 (0.44) | HRH3KCNH2ESR2HRH2HRH1 | |
| SCHEMBL9445453 | 0.87 | HRH3 (0.44) | HRH3KCNH2ESR2HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956548-B2 | Liquid crystal formulations and structures for smectic A optical devices | DOW CORNING CORPORATION (US) | 2015-02-17 | — | — | US | disclosed |
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |