SCHEMBL10909889

SCHEMBL10909889

O=[N+]([O-])c1ccc(-c2nc(-c3ccc([N+](=O)[O-])cc3)c(-c3ccc([N+](=O)[O-])cc3)s2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
ALDH1A1 P00352 2/20 0.62
PKM P14618 1/20 0.62
MAPK1 P28482 1/20 0.62
HTT P42858 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
APP P05067 3/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55
RAB9A P51151 1/20 0.55
MGAM O43451 1/20 0.51
GAA P10253 1/20 0.51
SI P14410 1/20 0.51
MGAM2 Q2M2H8 1/20 0.51
RECQL P46063 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11287831 0.94 KMT2A (0.72) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11752217 0.82 MAPT (0.61) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL3886944 0.82 MAPT (0.89) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL12491432 0.82 MAPT (0.61) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11748860 0.82 MAPT (0.61) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL13801090 0.79 APP (0.61) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11754079 0.78 MAPT (0.57) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11756967 0.78 MAPT (0.57) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11758890 0.77 KMT2A (0.71) MAPTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11748050 0.77 KMT2A (0.71) MAPTSMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4612271-A Photosensitive composition comprising azo compounds FUJI PHOTO FILM CO., LTD. (JP) 1986-09-16 US disclosed