Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098604 | 0.85 | BRD4 (0.35) | BRD4OPRM1TP53KMT2AALDH1A1 | |
| SCHEMBL11093637 | 0.84 | BRD4 (0.38) | BRD4OPRM1TP53KMT2AALDH1A1 | |
| SCHEMBL10909040 | 0.83 | BRD4 (0.34) | BRD4OPRM1TP53KMT2AALDH1A1 | |
| SCHEMBL11092386 | 0.82 | CNR1 (0.37) | BRD4OPRM1KMT2AALDH1A1MAPT | |
| SCHEMBL10733838 | 0.82 | KMT2A (0.38) | BRD4OPRM1KMT2AALDH1A1TDP1 | |
| SCHEMBL11098282 | 0.82 | BRD4 (0.37) | BRD4OPRM1TP53KMT2AALDH1A1 | |
| SCHEMBL10735397 | 0.79 | KDM4E (0.37) | BRD4OPRM1TP53KMT2AALDH1A1 | |
| SCHEMBL11094187 | 0.78 | MAPK1 (0.35) | BRD4OPRM1TP53KMT2AALDH1A1 | |
| SCHEMBL11097162 | 0.77 | BRD4 (0.40) | BRD4OPRM1TP53KMT2AALDH1A1 | |
| SCHEMBL11094830 | 0.77 | KDM4E (0.38) | BRD4KMT2AALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613617-A | Synergistic insecticidal compositions containing dione esters | UNION CARBIDE CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |