Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094931 | 0.85 | OPRM1 (0.39) | BRD4OPRM1TP53CYP2C19ALDH1A1 | |
| SCHEMBL11093637 | 0.85 | BRD4 (0.38) | BRD4OPRM1TP53CYP2C19ALDH1A1 | |
| SCHEMBL11091882 | 0.84 | BRD4 (0.36) | BRD4OPRM1TP53CYP2C19ALDH1A1 | |
| SCHEMBL11098282 | 0.83 | BRD4 (0.37) | BRD4OPRM1TP53CYP2C19ALDH1A1 | |
| SCHEMBL11090700 | 0.82 | ADORA3 (0.38) | BRD4OPRM1CYP2C19ALDH1A1MEN1 | |
| SCHEMBL11099865 | 0.80 | BRD4 (0.43) | BRD4OPRM1L3MBTL1 | |
| SCHEMBL10735397 | 0.80 | KDM4E (0.37) | BRD4OPRM1TP53CYP2C19ALDH1A1 | |
| SCHEMBL11098604 | 0.80 | BRD4 (0.35) | BRD4OPRM1TP53CYP2C19ALDH1A1 | |
| SCHEMBL11094187 | 0.79 | MAPK1 (0.35) | BRD4OPRM1TP53CYP2C19ALDH1A1 | |
| SCHEMBL11122094 | 0.79 | MEN1 (0.38) | BRD4OPRM1CYP2C19ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436666-A | HERBICIDES, MITICIDWS | UNION CARBIDE CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |