Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039217 | 1.00 | LMNA (0.33) | LMNA | |
| SCHEMBL1307768 | 1.00 | LMNA (0.33) | LMNA | |
| SCHEMBL5463398 | 1.00 | LMNA (0.33) | LMNA | |
| SCHEMBL28173111 | 1.00 | LMNA (0.33) | LMNA | |
| SCHEMBL10912363 | 0.97 | — | — | |
| SCHEMBL5468190 | 0.89 | — | — | |
| SCHEMBL10911492 | 0.82 | LMNA (0.32) | LMNA | |
| SCHEMBL10994750 | 0.82 | LMNA (0.32) | LMNA | |
| SCHEMBL10911481 | 0.79 | — | — | |
| SCHEMBL5461119 | 0.78 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114413-B1 | FLUORALKYLOXYALKYL-SUBSTITUENTS CONTAINING POLYDIORGANOPOLYSILOXANES, AND THEIR USE | Wacker-Chemie GmbH (DE) | 1986-11-26 | — | — | EP | disclosed |
| US-4549004-A | ANTIFOAM LUBRICANT | WACKER-CHEMIE GMBH (DE) | 1985-10-22 | — | — | US | disclosed |
| US-4489201-A | Fluoroalkyloxylakyl containing organopolysiloxanes | WACKER-CHEMIE GMBH (DE) | 1984-12-18 | — | — | US | disclosed |
| EP-0114413-A1 | Fluoralkyloxyalkyl-substituents containing polydiorganopolysiloxanes, and their use | Wacker-Chemie GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |