Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909820 | 0.94 | KDM4E (0.56) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10912256 | 0.88 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10911688 | 0.87 | KMT2A (0.61) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10912619 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10910054 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10909601 | 0.82 | CHRNB2 (0.46) | KDM4EALDH1A1KMT2AMEN1HTT | |
| Dimethylamine SCHEMBL10911945 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10911698 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10912048 | 0.80 | POLB (0.46) | KDM4EALDH1A1KMT2AMEN1HTT | |
| Diethylamine SCHEMBL10910059 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | claimed |
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |