Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 7/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | TYR | P14679 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.63 |
| ▸ | JAK2 | O60674 | 1/20 | 0.63 |
| ▸ | STK17B | O94768 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963493 | 0.87 | MEN1 (0.80) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL6963496 | 0.87 | MEN1 (0.80) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL11425146 | 0.86 | MAOB (0.72) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL10908277 | 0.86 | MEN1 (0.57) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL10909723 | 0.86 | STK17B (0.68) | MEN1KMT2AMAOBMAOARECQL | |
| SCHEMBL5707779 | 0.85 | MAOB (0.83) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL5707772 | 0.85 | MAOB (0.83) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL10933295 | 0.83 | MAOB (0.66) | MEN1KMT2AMAOBRECQLKDM4E | |
| SCHEMBL10893599 | 0.83 | MEN1 (0.67) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL28949983 | 0.82 | MEN1 (0.74) | MEN1KMT2AUSP2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32196-E | PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS | LILLY INDUSTRIES LIMITED (GB) | 1986-07-01 | — | — | US | disclosed |
| US-4259340-A | PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS SUCH AS ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1981-03-31 | — | — | US | disclosed |