Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | USP2 | O75604 | 2/20 | 0.80 |
| ▸ | CASP3 | P42574 | 1/20 | 0.80 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.80 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.80 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.80 |
| ▸ | MAOB | P27338 | 9/20 | 0.76 |
| ▸ | MAOA | P21397 | 2/20 | 0.76 |
| ▸ | TYR | P14679 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.72 |
| ▸ | AURKA | O14965 | 1/20 | 0.72 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.72 |
| ▸ | JAK2 | O60674 | 1/20 | 0.72 |
| ▸ | STK17B | O94768 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963496 | 1.00 | MEN1 (0.80) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL5707772 | 0.90 | MAOB (0.83) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL5707779 | 0.90 | MAOB (0.83) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL30214393 | 0.89 | MEN1 (0.74) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL28949983 | 0.89 | MEN1 (0.74) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL30214420 | 0.89 | MEN1 (0.74) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL6959091 | 0.88 | MAOB (0.82) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL6965152 | 0.88 | MAOB (0.78) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL6965147 | 0.88 | MAOB (0.78) | MEN1KMT2AUSP2CASP3SENP8 | |
| SCHEMBL6959099 | 0.88 | MAOB (0.82) | MEN1KMT2AUSP2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902022-A1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |