Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213803 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6214790 | 0.90 | KDM4E (0.49) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10912940 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10911343 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9868878 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6215098 | 0.85 | PIM1 (0.43) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10915726 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10915439 | 0.83 | HPGD (0.47) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10915500 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10914437 | 0.82 | HPGD (0.45) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |