Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10915432 | 0.99 | KMT2A (0.69) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10911419 | 0.90 | KMT2A (0.69) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10912500 | 0.90 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10915293 | 0.89 | KMT2A (0.68) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10911607 | 0.89 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10914654 | 0.87 | KMT2A (0.65) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10914832 | 0.86 | KMT2A (0.64) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10911705 | 0.83 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL10914663 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10980799 | 0.82 | KMT2A (0.59) | KMT2AMEN1ALDH1A1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | claimed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | claimed |
| EP-0064878-A1 | Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | claimed |
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0064878-A1 | Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |