Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886868 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL16754925 | 0.77 | GSK3B (0.62) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL29485716 | 0.74 | GSK3B (0.52) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL112742 | 0.74 | GSK3B (0.52) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL166123 | 0.73 | HPGD (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL17726916 | 0.73 | MEN1 (0.57) | KDM4EALDH1A1HPGDHSD17B10GSK3B | |
| SCHEMBL29025704 | 0.72 | GSK3B (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Hydrochloric Acid SCHEMBL29864773 | 0.72 | GSK3B (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL30364460 | 0.72 | GSK3B (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Hydrochloric Acid SCHEMBL7736928 | 0.72 | GSK3B (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043630-B1 | IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS | GIST-BROCADES N.V. (NL) | 1986-01-08 | — | — | EP | disclosed |