SCHEMBL112742

SCHEMBL112742

Cc1cccc2c1C(=O)NC2=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.52
DAO P14920 1/20 0.52
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
PARP1 P09874 6/20 0.48
CASP3 P42574 2/20 0.45
CASP7 P55210 2/20 0.45
CASP2 P42575 1/20 0.45
CASP6 P55212 1/20 0.45
CASP8 Q14790 1/20 0.45
POLB P06746 3/20 0.44
MEN1 O00255 1/20 0.44
RGS12 O14924 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485716 1.00 GSK3B (0.52) GSK3BDAOKDM4EALDH1A1GAA
SCHEMBL29025704 0.98 GSK3B (0.50) GSK3BDAOKDM4EALDH1A1GAA
SCHEMBL30364460 0.98 GSK3B (0.50) GSK3BDAOKDM4EALDH1A1GAA
Hydrochloric Acid SCHEMBL7736928 0.98 GSK3B (0.50) GSK3BDAOKDM4EALDH1A1GAA
Hydrochloric Acid SCHEMBL29864773 0.98 GSK3B (0.50) GSK3BDAOKDM4EALDH1A1GAA
Phthalimide SCHEMBL8855990 0.96 GSK3B (0.60) GSK3BDAOKDM4EALDH1A1GAA
Dimethylamine SCHEMBL3813435 0.94 KDM4E (0.51) GSK3BDAOKDM4EALDH1A1GAA
SCHEMBL28989737 0.89 KDM4E (0.44) GSK3BDAOKDM4EALDH1A1GAA
SCHEMBL22525286 0.88 DAO (0.58) GSK3BDAOKDM4EALDH1A1GAA
SCHEMBL22904118 0.86 GSK3B (0.52) GSK3BDAOKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 628 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP claimed
CN-115991685-B Preparation method of oxetane-2-methylamine 韶远科技(上海)有限公司 2025-03-04 CN claimed
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN claimed
CN-118084674-A Method for preparing deuterated methylamine hydrochloride by using methyl triflate-D3 西安瑞联新材料股份有限公司 2024-05-28 CN claimed
CN-117342998-A Diamine monomer containing N-aminophthalimide structure, preparation method thereof, polyimide compound and application 浙江工业大学 2024-01-05 CN claimed
US-20230303578-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE (BEIJING) CO., LTD. (CN) 2023-09-28 US claimed
EP-4206205-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND Primegene (Beijing) Co., Ltd. (CN) 2023-07-05 EP claimed
US-20230151236-A1 MAGENTA PIGMENT DISPERSANTS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2023-05-18 US claimed
CN-115991685-A Preparation method of oxetane-2-methylamine 韶远科技(上海)有限公司 2023-04-21 CN claimed
EP-4143157-A1 METHODS OF MANUFACTURE OF DIANHYDRIDES Chaulagain, Mani (US) 2023-03-08 EP claimed
CN-101021511-A Method for detecting purity of 3,5 substituted oxazolidones compound SICHUAN BEILIKE BIOTECHNIC CO (CN) 2007-08-22 CN claimed
CN-101021487-A Method for assaying 3,5-substituted oxazolidones compound content SICHUAN BEILIKE BIOTECHNIC CO (CN) 2007-08-22 CN claimed
CN-101021512-A Method for detecting content of 3,5-substituted oxaolidones compound SICHUAN BEILIKE BIOTECHNICS CO (CN) 2007-08-22 CN claimed
US-7053129-B1 Process for preparing monodisperse anion exchangers BAYER AKTIENGESELLSCHAFT (DE) 2006-05-30 US claimed
US-6649663-B1 Addition copolymerizing and crosslinking monovinylaromatic compound and polyvinylaromatic compound; amidomethylating with phthalimide or methylphthalimide BAYER AKTIENGESELLSCHAFT (DE) 2003-11-18 US claimed
US-6329435-B1 REACTING MONOMER DROPLETS OF MONOVINYLAROMATIC COMPOUND AND POLYVINYLAROMATIC COMPOUND TO GIVE BEAD POLYMER; AMIDOMETHYLATING, CONVERTING TO AMINOMETHYLATED BEAD POLYMER, REACTING WITH THIOUREA OR ITS DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 2001-12-11 US claimed
EP-0299421-B1 Imide modified epoxy resins DOW CHEMICAL CO (US) 1996-03-13 EP claimed
US-4847348-A BINDERS, COATINGS THE DOW CHEMICAL COMPANY (US) 1989-07-11 US claimed
EP-0299421-A2 Imide modified epoxy resins THE DOW CHEMICAL COMPANY (US) 1989-01-18 EP claimed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303578-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND DPYD, RPLP2, DHPS GSK3B 3303/4885DAO 2589/4885KDM4E 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.