SCHEMBL10914740

SCHEMBL10914740

CC1(C)OC(=O)Nc2ccc(OCCCCl)cc21

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGR P06401 20/20 0.52
AR P10275 4/20 0.48
NR3C1 P04150 3/20 0.48
NR3C2 P08235 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10917088 0.96 PGR (0.51) PGRARNR3C1NR3C2
SCHEMBL10962864 0.95 PGR (0.52) PGRARNR3C1NR3C2
SCHEMBL10916763 0.87 PGR (0.48) PGRARNR3C1NR3C2
SCHEMBL10918924 0.86 PGR (0.47) PGRARNR3C1NR3C2
SCHEMBL10917221 0.86 PGR (0.47) PGRARNR3C1NR3C2
SCHEMBL10919088 0.85 PGR (0.46) PGRARNR3C1NR3C2
SCHEMBL10920884 0.84 PGR (0.46) PGRARNR3C1NR3C2
SCHEMBL10993699 0.84 PGR (0.46) PGRARNR3C1NR3C2
SCHEMBL10916053 0.83 PGR (0.45) PGRARNR3C1NR3C2
SCHEMBL10918201 0.81 PGR (0.54) PGRARNR3C1NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0093922-B1 BENZOXAZIN-2-ONES, THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS Dr. Karl Thomae GmbH (DE) 1986-12-30 EP disclosed
US-4518597-A THROMBOSIS, ARTERIOSCLEROSIS, ANTITUMOR, ANTICOAGULANTS DR. KARL THOMAE GMBH (DE) 1985-05-21 US disclosed
EP-0093922-A2 Benzoxazin-2-ones, their preparation and therapeutic agents containing these compounds Dr. Karl Thomae GmbH (DE) 1983-11-16 EP disclosed