Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 9/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869366 | 0.89 | KDM4E (0.54) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10912098 | 0.86 | KDM4E (0.43) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10911561 | 0.86 | KDM4E (0.44) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9636639 | 0.82 | MEN1 (0.55) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10913865 | 0.81 | KDM4E (0.59) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10374458 | 0.81 | HPGD (0.59) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10913415 | 0.80 | KDM4E (0.56) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9047556 | 0.80 | KDM4E (0.55) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9044502 | 0.78 | LMNA (0.40) | HPGDKDM4EHSD17B10ALDH1A1TOP2A | |
| Hydrochloric Acid SCHEMBL9035741 | 0.77 | LMNA (0.45) | HPGDKDM4EHSD17B10ALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |