Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | TNF | P01375 | 2/20 | 0.63 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491417 | 0.82 | TNF (0.66) | RAB9ATNFNOD1SMN1; SMN2NPC1 | |
| SCHEMBL6123117 | 0.80 | RAB9A (0.59) | RAB9ATNFNOD1SMN1; SMN2NPC1 | |
| SCHEMBL11256846 | 0.79 | NR2F2 (0.59) | RAB9ASMN1; SMN2NPC1KMT2ATSHR | |
| SCHEMBL1904096 | 0.78 | TNF (1.00) | RAB9ATNFNOD1NPC1FDPS | |
| SCHEMBL8506455 | 0.77 | RAB9A (0.58) | RAB9ATNFNOD1SMN1; SMN2NPC1 | |
| SCHEMBL9609193 | 0.77 | RAB9A (0.58) | RAB9ATNFNOD1SMN1; SMN2NPC1 | |
| SCHEMBL11413904 | 0.76 | RAB9A (0.68) | RAB9ATNFNOD1NPC1MEN1 | |
| SCHEMBL8505866 | 0.76 | KMT2A (0.68) | RAB9ATNFNOD1SMN1; SMN2NPC1 | |
| SCHEMBL8516404 | 0.76 | RAB9A (0.57) | RAB9ATNFNOD1SMN1; SMN2NPC1 | |
| SCHEMBL8490752 | 0.76 | RAB9A (0.57) | RAB9ATNFNOD1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103114-B1 | THIENOPYRIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4562193-A | 4-[2-(Di- or trisubstitutedphenoxy)ethyl amino]thienodipyrimidines and insecticidal and acaricidal composition containing said pyrimidines | SANKYO COMPANY LIMITED (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0103114-A2 | Thienopyridine derivatives, their preparation and insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1984-03-21 | — | — | EP | disclosed |