Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913488 | 0.91 | KMT2A (0.60) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10914090 | 0.89 | KMT2A (0.58) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10975714 | 0.84 | KDM4E (0.51) | KDM4ETSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL10911236 | 0.84 | KMT2A (0.59) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10911705 | 0.84 | ALDH1A1 (0.63) | KDM4ETSHRMAPK1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10914663 | 0.83 | ALDH1A1 (0.62) | KDM4ETSHRMAPK1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10911309 | 0.83 | CHEK1 (0.58) | KDM4ETSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10914273 | 0.82 | ALDH1A1 (0.61) | KDM4ETSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL31520487 | 0.80 | MEN1 (0.68) | KDM4ETSHRALDH1A1CYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10911285 | 0.80 | TSHR (0.56) | KDM4ETSHRMAPK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0064878-A1 | Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |