Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479578 | 0.98 | FDPS (0.35) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL6152478 | 0.94 | — | — | |
| SCHEMBL10900101 | 0.82 | FDPS (0.39) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL28803556 | 0.82 | FDPS (0.41) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL31648195 | 0.80 | FDPS (0.43) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL11257292 | 0.79 | — | — | |
| SCHEMBL2754123 | 0.78 | FDPS (0.39) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL11268801 | 0.76 | — | — | |
| SCHEMBL8433925 | 0.75 | TSHR (0.38) | FDPSGGPS1TSHR | |
| SCHEMBL27690967 | 0.75 | FDPS (0.39) | FDPSGGPS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061197-B1 | ALPHA CHAIN DIENIC PROSTANOIC ACID DERIVATIVES | G.D. Searle & Co. (US) | 1986-05-21 | — | — | EP | disclosed |
| EP-0061197-A1 | Alpha chain dienic prostanoic acid derivatives | G.D. Searle & Co. (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4312994-A | α Chain dienic prostanoic acid derivatives | G. D. SEARLE & CO. (US) | 1982-01-26 | — | — | US | disclosed |