Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916737 | 1.00 | NAAA (0.44) | NAAAPREPALDH1A1GAACA12 | |
| SCHEMBL10676450 | 0.90 | CA12 (0.46) | NAAAPREPALDH1A1GAACA12 | |
| SCHEMBL10676435 | 0.90 | CA12 (0.46) | NAAAPREPALDH1A1GAACA12 | |
| SCHEMBL10836698 | 0.83 | CA12 (0.46) | NAAAPREPALDH1A1GAACA12 | |
| SCHEMBL10837391 | 0.83 | CA12 (0.49) | NAAAPREPALDH1A1GAACA12 | |
| SCHEMBL10836705 | 0.83 | CA12 (0.46) | NAAAPREPALDH1A1GAACA12 | |
| SCHEMBL10837380 | 0.83 | CA12 (0.49) | NAAAPREPALDH1A1GAACA12 | |
| SCHEMBL10832788 | 0.83 | PREP (0.52) | NAAAPREPALDH1A1GAACTSL | |
| SCHEMBL10832792 | 0.83 | PREP (0.52) | NAAAPREPALDH1A1GAACTSL | |
| SCHEMBL9740624 | 0.82 | NAAA (0.55) | NAAAPREPALDH1A1GAACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062876-B1 | 2-OXO-1-(((SUBSTITUTED SULFONYL)AMINO)CARBONYL)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1986-09-24 | — | — | EP | disclosed |
| EP-0062876-A1 | 2-Oxo-1-(((substituted sulfonyl)amino)carbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1982-10-20 | — | — | EP | disclosed |