Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 7/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PLAT | P00750 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918392 | 0.81 | PLAU (0.49) | PLAUF2F10PLGPRSS1 | |
| SCHEMBL7341983 | 0.80 | F12 (0.56) | PLAUF2F10PLGPRSS1 | |
| Bicarbonate SCHEMBL10918389 | 0.78 | PLAU (0.54) | PLAUF2F10PLGPRSS1 | |
| Bicarbonate SCHEMBL7341573 | 0.78 | PLAU (0.54) | PLAUF2F10PLGPRSS1 | |
| Acetic Acid SCHEMBL7340710 | 0.77 | PLAU (0.53) | PLAUF2F10PLGPRSS1 | |
| SCHEMBL10856126 | 0.73 | PLG (0.61) | PLAUF2F10PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL10595979 | 0.71 | PLG (0.59) | PLAUF2F10PLGPRSS1 | |
| SCHEMBL31307550 | 0.71 | KMT2A (0.51) | — | |
| SCHEMBL9854041 | 0.71 | KMT2A (0.51) | — | |
| SCHEMBL7347944 | 0.70 | PLAU (0.44) | PLAUF2F10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048433-B1 | NOVEL AMIDINE COMPOUNDS, PROCESS FOR PRODUCING SAME AND ANTI-COMPLEMENT AGENT COMPRISING THEM | TORII & CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |
| US-4532255-A | Amidine compounds and anticomplement agent comprising same | TORII & CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | disclosed |