Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MB | P02144 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31180367 | 0.80 | HTR2A (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL20597396 | 0.76 | PARP1 (0.38) | MBCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL20714433 | 0.73 | PDE7A (0.39) | MBCYP3A4MAPK1PSMB5 | |
| SCHEMBL31180313 | 0.72 | HTR5A (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL286755 | 0.70 | KCNJ1 (0.44) | CYP3A4MAPK1PSMB5 | |
| SCHEMBL10916724 | 0.69 | CYP11B1 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL3604854 | 0.67 | CYP11B1 (0.36) | MBCYP11B1CYP11B2 | |
| SCHEMBL25190883 | 0.67 | CYP11B1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL7565735 | 0.67 | MB (0.39) | MBCYP11B1CYP11B2 | |
| SCHEMBL10916352 | 0.67 | CYP11B1 (0.40) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093922-B1 | BENZOXAZIN-2-ONES, THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1986-12-30 | — | — | EP | disclosed |
| US-4518597-A | THROMBOSIS, ARTERIOSCLEROSIS, ANTITUMOR, ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1985-05-21 | — | — | US | disclosed |
| EP-0093922-A2 | Benzoxazin-2-ones, their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-11-16 | — | — | EP | disclosed |