Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317354 | 0.88 | — | — | |
| SCHEMBL14580212 | 0.73 | — | — | |
| SCHEMBL4900394 | 0.72 | PIK3CD (0.40) | PIK3CD | |
| SCHEMBL12748060 | 0.71 | — | — | |
| SCHEMBL6365551 | 0.70 | — | — | |
| SCHEMBL6366119 | 0.70 | — | — | |
| SCHEMBL18686730 | 0.68 | L3MBTL1 (0.38) | — | |
| SCHEMBL82607 | 0.65 | — | — | |
| Alcohol SCHEMBL28282515 | 0.65 | BRD4 (0.37) | BRD4PIK3CDCHRNB2CHRNA4BRD2 | |
| SCHEMBL15370383 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547271-A | IN PRESENCE OF WEAKLY ACIDIC, HIGHLY POLAR SOLVENT TO PROMOTE STEREOSELECTIVITY | CANADA PACKERS INC. (CA) | 1985-10-15 | — | — | US | disclosed |