Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.64 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.55 |
| ▸ | APEX1 | P27695 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922212 | 1.00 | FAP (0.66) | FAPMAPTNR1I2ALBPPARG | |
| SCHEMBL10920988 | 0.93 | MAPT (0.74) | FAPMAPTNR1I2ALBPPARG | |
| SCHEMBL10920191 | 0.93 | MAPT (0.74) | FAPMAPTNR1I2ALBPPARG | |
| Cefcapene SCHEMBL419455 | 0.92 | FAP (0.77) | FAPMAPTNR1I2ALBPPARG | |
| Cefcapene SCHEMBL419454 | 0.92 | FAP (0.77) | FAPMAPTNR1I2ALBPPARG | |
| SCHEMBL10920264 | 0.92 | MAPT (0.73) | FAPMAPTNR1I2ALBPPARG | |
| Cefcapene SCHEMBL419453 | 0.92 | FAP (0.77) | FAPMAPTNR1I2ALBPPARG | |
| Cefcapene SCHEMBL2828956 | 0.92 | FAP (0.79) | FAPMAPTNR1I2ALBPPARG | |
| Cefcapene SCHEMBL2828959 | 0.92 | FAP (0.79) | FAPMAPTNR1I2ALBPPARG | |
| Cefcapene SCHEMBL27739649 | 0.92 | FAP (0.76) | FAPMAPTNR1I2ALBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048954-B1 | BETA-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | claimed |
| EP-0048954-A2 | Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-04-07 | — | — | EP | claimed |
| EP-0048954-A2 | Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-04-07 | — | — | EP | disclosed |