Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939859 | 0.90 | TSHR (0.62) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL10943632 | 0.90 | TSHR (0.60) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL24462646 | 0.87 | HPGD (0.39) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL5587049 | 0.84 | HPGD (0.44) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL5590229 | 0.84 | TSHR (0.53) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL10577820 | 0.83 | TSHR (0.50) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL3221262 | 0.80 | HPGD (0.39) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL6063823 | 0.80 | TSHR (0.56) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL17490271 | 0.79 | HPGD (0.44) | HPGDHSD17B10TSHRALDH1A1MAPT | |
| SCHEMBL5587483 | 0.79 | HPGD (0.44) | HPGDHSD17B10TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596880-A | Pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | disclosed |
| US-4438275-A | 2,2-DIFLUORO-BENZODIOXOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |
| US-4310540-A | PYRETHROID-LIKE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |