SCHEMBL5590229

SCHEMBL5590229

Cc1c(O)c(O)c(Cl)c(Cl)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
HPGD P15428 5/20 0.53
HSD17B10 Q99714 5/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 2/20 0.53
LMNA P02545 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 4/20 0.36
CYP2C9 P11712 4/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 3/20 0.35
MAPK1 P28482 3/20 0.34
CYP3A4 P08684 3/20 0.33
ALOX15 P16050 2/20 0.33
CHRM1 P11229 1/20 0.33
MAOA P21397 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063823 0.90 TSHR (0.56) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL5587483 0.90 HPGD (0.44) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL5587049 0.88 HPGD (0.44) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL10922334 0.84 HPGD (0.47) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL3221262 0.84 HPGD (0.39) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL22931524 0.81 TSHR (0.53) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL10939859 0.81 TSHR (0.62) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL3308498 0.81 TSHR (0.44) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL11060919 0.81 HPGD (0.37) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL10943632 0.80 TSHR (0.60) TSHRHPGDHSD17B10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 TSHR 4680/4885HPGD 2689/4885HSD17B10 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.