Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 2/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919597 | 0.93 | KMT2A (0.90) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Teflubenzuron SCHEMBL29352804 | 0.90 | KMT2A (1.00) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Teflubenzuron SCHEMBL26635 | 0.90 | KMT2A (1.00) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Teflubenzuron SCHEMBL4217571 | 0.90 | KMT2A (1.00) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL9325645 | 0.88 | KMT2A (0.95) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10922698 | 0.85 | MEN1 (0.68) | KMT2AMEN1PPIAPYGLCYP1A2 | |
| Teflubenzuron SCHEMBL9985834 | 0.83 | MEN1 (0.84) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10922399 | 0.81 | MEN1 (0.56) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL8840240 | 0.81 | MEN1 (0.56) | KMT2AMEN1MAPTPPIAGHSR | |
| SCHEMBL7604187 | 0.81 | MEN1 (0.55) | KMT2AMEN1MAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622340-A | HALOGENATED PHENYL HALOGENATED BENZOYL UREA, INSECTICIDES, FUNGICIDES | CELAMERCK GMBH & CO., KG (DE) | 1986-11-11 | — | — | US | disclosed |
| US-4457943-A | INSECTICIDES, MITICIDES | CELAMERCK GMBH & CO. KG (DE) | 1984-07-03 | — | — | US | disclosed |