Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.95 |
| ▸ | MEN1 | O00255 | 4/20 | 0.95 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Teflubenzuron SCHEMBL26635 | 0.97 | KMT2A (1.00) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Teflubenzuron SCHEMBL4217571 | 0.97 | KMT2A (1.00) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Teflubenzuron SCHEMBL29352804 | 0.97 | KMT2A (1.00) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10919597 | 0.92 | KMT2A (0.90) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Teflubenzuron SCHEMBL9985834 | 0.89 | MEN1 (0.84) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10923554 | 0.88 | KMT2A (0.82) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10390653 | 0.88 | KMT2A (0.82) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Teflubenzuron SCHEMBL1899156 | 0.85 | MEN1 (0.77) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10384014 | 0.85 | MEN1 (0.77) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10720041 | 0.83 | KMT2A (0.74) | KMT2AMEN1MAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155135-A | Insecticides, miticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) | 1992-10-13 | — | — | US | claimed |
| EP-0375069-B1 | Benzamide compounds, their preparation and their use as pesticides | SHELL INT RESEARCH (NL) | 1994-03-09 | — | — | EP | disclosed |
| US-5155135-A | Insecticides, miticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) | 1992-10-13 | — | — | US | disclosed |
| EP-0375069-A1 | Benzamide compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-06-27 | — | — | EP | disclosed |