Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920078 | 0.92 | TMEM97 (0.43) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL10917745 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11402421 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11402417 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL10925171 | 0.81 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11040893 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11399476 | 0.78 | TMEM97 (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL29280659 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL27962229 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL10922438 | 0.77 | KMT2A (0.48) | SMN1; SMN2LMNAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595531-A | Thermal treatment of benzodiazocine in an inert solvent in the presence of a nucleophilic agent or with a halogenating Lewis acid | KALI-CHEMIE AG (DE) | 1986-06-17 | — | — | US | disclosed |
| US-4216167-A | INTERMEDIATE FOR DIAZEPINES | KALI-CHEMIE AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
| US-4096141-A | CYCLIZATION OF AN ACYLDIAMINE, PHOSPHORUS OXYHALIDE | KALI-CHEMIE AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3998809-A | ANTICONVULSANTS, SEDATIVES, MUSCLE RELAXANTS, TRANQUILIZERS | KALI-CHEMIE AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |