Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922977 | 1.00 | MEN1 (0.71) | MEN1POLBKMT2AEPHX2NPC1 | |
| SCHEMBL10926918 | 0.99 | MEN1 (0.69) | MEN1POLBKMT2AEPHX2NPC1 | |
| SCHEMBL10553825 | 0.84 | KMT2A (1.00) | MEN1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL10921358 | 0.84 | KMT2A (1.00) | MEN1POLBKMT2AMAPTALDH1A1 | |
| Bromide SCHEMBL10556088 | 0.83 | KMT2A (0.97) | MEN1POLBKMT2AMAPTALDH1A1 | |
| Bromide SCHEMBL10553700 | 0.83 | KMT2A (0.97) | MEN1POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL10923255 | 0.83 | KMT2A (0.97) | MEN1POLBKMT2ANPC1RAB9A | |
| SCHEMBL3044695 | 0.82 | FAAH (0.62) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL10555741 | 0.81 | KMT2A (0.94) | MEN1POLBKMT2ANPC1RAB9A | |
| SCHEMBL321314 | 0.80 | NOX1 (0.62) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180994-A2 | Antihypertensive dialkyl aminoethylaniline derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-05-14 | — | — | EP | disclosed |