Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 5/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921272 | 0.89 | S1PR3 (0.41) | S1PR3S1PR1POLBKMT2AGRN | |
| SCHEMBL10921455 | 0.85 | GRN (0.46) | S1PR3S1PR1POLBKMT2AGRN | |
| SCHEMBL10924508 | 0.75 | POLB (0.40) | S1PR3POLBKMT2AGRNSORT1 | |
| SCHEMBL9793809 | 0.74 | GRN (0.44) | GRNSORT1 | |
| SCHEMBL9532631 | 0.73 | ALDH1A1 (0.36) | KMT2A | |
| SCHEMBL3809482 | 0.68 | KMT2A (0.45) | POLBKMT2A | |
| SCHEMBL11450361 | 0.67 | GRN (0.56) | GRNSORT1 | |
| SCHEMBL10805444 | 0.65 | ALDH1A1 (0.63) | POLB | |
| SCHEMBL10923977 | 0.65 | ALDH1A1 (0.41) | S1PR3S1PR1 | |
| SCHEMBL9371157 | 0.65 | KMT2A (0.46) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061836-B1 | AMIDE DERIVATIVES, PROCESSES FOR PREPARING THEM, THEIR USE AS FUNGICIDES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4506084-A | N-HETEROCYCLYLEMTHYL AMIDES, HERBICIDES, FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-19 | — | — | US | disclosed |
| US-4432784-A | HERBICIDES, FUNGICIDES WHICH ARE N-HETEROCYCLYLMETHYL AMIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-02-21 | — | — | US | disclosed |
| EP-0061836-A2 | Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-10-06 | — | — | EP | disclosed |