Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632758 | 0.86 | HTT (0.44) | HTTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29826849 | 0.86 | HTT (0.44) | HTTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Propane SCHEMBL10851565 | 0.83 | KMT2A (0.39) | HTTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Propane SCHEMBL10920259 | 0.78 | ALDH1A1 (0.47) | HTTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Propane SCHEMBL10860075 | 0.78 | KMT2A (0.35) | HTTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Propane SCHEMBL10918212 | 0.76 | SMN1; SMN2 (0.40) | HTTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Propane SCHEMBL10852960 | 0.76 | KMT2A (0.34) | LMNAKMT2AALDH1A1 | |
| Propane SCHEMBL10922828 | 0.76 | TDP1 (0.48) | HTTLMNAKMT2AALDH1A1MAPK1 | |
| SCHEMBL11075995 | 0.75 | HTT (0.35) | HTTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| Propane SCHEMBL10853768 | 0.75 | PDE10A (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114045-B1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-09-03 | — | — | EP | claimed |