Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20539302 | 0.80 | NOTUM (0.47) | PARP10PARP11S1PR1S1PR3NOTUM | |
| SCHEMBL30916119 | 0.80 | NOTUM (0.47) | PARP10PARP11S1PR1S1PR3NOTUM | |
| SCHEMBL29648250 | 0.79 | PARP10 (0.64) | PARP10PARP11S1PR1S1PR3NOTUM | |
| SCHEMBL4718535 | 0.79 | PARP10 (0.64) | PARP10PARP11S1PR1S1PR3NOTUM | |
| SCHEMBL15312190 | 0.76 | PARP10 (0.47) | PARP10PARP11S1PR1S1PR3NOTUM | |
| SCHEMBL31121854 | 0.76 | PARP10 (0.47) | PARP10PARP11S1PR1S1PR3NOTUM | |
| SCHEMBL30421356 | 0.75 | PARP10 (0.44) | PARP10PARP11S1PR1S1PR3PARP1 | |
| SCHEMBL10921073 | 0.75 | PARP10 (0.48) | PARP10PARP11NOTUMNUDT1 | |
| SCHEMBL30422322 | 0.75 | PARP1 (0.50) | PARP10PARP11S1PR1S1PR3PARP1 | |
| SCHEMBL30421478 | 0.75 | PARP10 (0.48) | PARP10PARP11NOTUMNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089426-B1 | 2-AMINO-6-BIPHENYLACETIC ACIDS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-06-11 | — | — | EP | disclosed |