Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.76 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.76 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.76 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.76 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.76 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.76 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.65 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14543642 | 0.87 | F2 (1.00) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL23541143 | 0.85 | F2 (1.00) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL48986 | 0.85 | PRSS1 (0.57) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7449474 | 0.82 | F2 (0.89) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7442771 | 0.82 | F2 (0.89) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10922350 | 0.81 | F2 (0.86) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6629683 | 0.79 | F2 (0.83) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL7317832 | 0.79 | F2 (0.79) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL14599535 | 0.79 | F2 (0.76) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL23566292 | 0.79 | PRSS1 (1.00) | F2PRSS1PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598077-A | Amidine derivatives and cardiotonic compositions | TORII & CO. LTD. (JP) | 1986-07-01 | — | — | US | disclosed |