Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10553254 | 0.99 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10921930 | 0.90 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| Bromide SCHEMBL10552105 | 0.88 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10921780 | 0.87 | ESR1 (0.38) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| Bromide SCHEMBL10554450 | 0.86 | ESR1 (0.37) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10919555 | 0.84 | ALOX5 (0.49) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL6261729 | 0.84 | TP53 (0.58) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| Bromide SCHEMBL10557453 | 0.83 | ALOX5 (0.48) | MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27349395 | 0.82 | TP53 (0.56) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10926432 | 0.79 | TP53 (0.53) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180994-A2 | Antihypertensive dialkyl aminoethylaniline derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-05-14 | — | — | EP | disclosed |