SCHEMBL10927757

SCHEMBL10927757

[CH]c1ccc(OC)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
GAA P10253 1/20 0.44
ACHE P22303 2/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2A6 P11509 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
HTR3A P46098 1/20 0.42
HTR3D Q70Z44 1/20 0.42
HTR3C Q8WXA8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10927763 1.00 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL29352597 0.77 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL83318 0.77 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL113300 0.76 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL113301 0.76 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL12326180 0.75 CA1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL29096230 0.75 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL82486 0.73 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL3640883 0.73 ALDH1A1 (0.61) CA12CA1CA2CA7CA9
SCHEMBL2090961 0.71 CA12 (0.62) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60051157-A None JP disclosed
JP-S6051157-A 4-ALKOXY-2-METHYLBENZYLIDENE DERIVATIVE RICOH CO LTD 1985-03-22 JP disclosed