Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 17/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 17/20 | 0.64 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10927385 | 0.83 | AKR1A1 (0.82) | AKR1A1AKR1B1 | |
| SCHEMBL9672105 | 0.80 | AKR1A1 (0.68) | AKR1A1AKR1B1 | |
| Imirestat SCHEMBL30924520 | 0.80 | AKR1A1 (1.00) | AKR1A1AKR1B1 | |
| Imirestat SCHEMBL49034 | 0.80 | AKR1A1 (1.00) | AKR1A1AKR1B1 | |
| SCHEMBL9751204 | 0.79 | AKR1A1 (0.66) | AKR1A1AKR1B1 | |
| SCHEMBL25892752 | 0.77 | AKR1A1 (0.76) | AKR1A1AKR1B1 | |
| SCHEMBL10929989 | 0.76 | AKR1B1 (0.56) | AKR1A1AKR1B1PDK2 | |
| SCHEMBL9810984 | 0.74 | AKR1A1 (0.88) | AKR1A1AKR1B1 | |
| SCHEMBL9672056 | 0.74 | AKR1A1 (0.76) | AKR1A1AKR1B1 | |
| SCHEMBL9672999 | 0.74 | AKR1A1 (0.76) | AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537892-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1985-08-27 | — | — | US | claimed |