Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928865 | 0.86 | MCHR1 (0.57) | RAB9ANPC1GAAMAPTHPGD | |
| SCHEMBL5388983 | 0.86 | TRPV1 (0.55) | RAB9ANPC1HTTGAATRPV1 | |
| SCHEMBL10930580 | 0.86 | KCNK3 (0.53) | RAB9ANPC1HTTGAAKMT2A | |
| SCHEMBL9764719 | 0.85 | TRPV1 (0.56) | RAB9ANPC1HTTGAATRPV1 | |
| SCHEMBL10929245 | 0.84 | CHRM3 (0.57) | KMT2AMEN1SLC2A1HPGDALDH1A1 | |
| SCHEMBL17740375 | 0.83 | RAB9A (0.76) | RAB9ANPC1HTTGAAKMT2A | |
| SCHEMBL10349147 | 0.83 | TRPV1 (0.47) | RAB9AHTTGAATRPV1ACKR3 | |
| SCHEMBL10927769 | 0.81 | KMT2A (0.58) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL10349077 | 0.80 | HPGD (0.55) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL10349181 | 0.79 | MCHR1 (0.57) | RAB9ANPC1HTTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113778-A4 | ARYL SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES USEFUL AS ANTIARRHYTHMIC AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1985-06-06 | — | — | EP | disclosed |
| EP-0113778-A1 | ARYL SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES USEFUL AS ANTIARRHYTHMIC AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-07-25 | — | — | EP | disclosed |
| WO-1984000545-A1 | ARYL SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES USEFUL AS ANTIARRHYTHMIC AGENTS | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-02-16 | — | — | WO | disclosed |