Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493074 | 0.95 | MAPT (0.34) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10933402 | 0.92 | MAPT (0.35) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10493190 | 0.90 | MAPT (0.37) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10635119 | 0.90 | MEN1 (0.39) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10702686 | 0.87 | LMNA (0.31) | MEN1KMT2ACCKBRLMNA | |
| SCHEMBL10493034 | 0.85 | MAPT (0.36) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10834483 | 0.85 | MAPT (0.36) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10833876 | 0.85 | MAPT (0.33) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10996640 | 0.84 | MAPT (0.34) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10996886 | 0.84 | MEN1 (0.38) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131611-A1 | $g(b)-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1985-01-23 | — | — | EP | disclosed |
| WO-1984002911-A1 | beta-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1984-08-02 | — | — | WO | disclosed |