Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878010 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL11258062 | 0.78 | CSNK2A1 (0.52) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL10760134 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL13484134 | 0.75 | CSNK2A1 (0.56) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL30307775 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL10768287 | 0.72 | CSNK2A2 (0.44) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL30353210 | 0.72 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL5194351 | 0.72 | CSNK2A2 (0.50) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL10756931 | 0.72 | KDM4E (0.45) | KDM4EALDH1A1HPGDHTTCSNK2A2 | |
| SCHEMBL3812191 | 0.72 | CSNK2A2 (0.49) | KDM4EALDH1A1HPGDHTTCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60166687-A | — | — | None | — | — | JP | disclosed |
| JP-S60166687-A | 5-FLUORO-3,4,7,10-TETRAHYDRO-7-OXO-2H-PYRIDO(3,2-H)-1,4- BENZOXAZINE-8-CARBOXYLIC ACID DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1985-08-29 | — | — | JP | disclosed |