Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083304 | 0.88 | ALDH1A1 (0.50) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL10874963 | 0.87 | CHRM2 (0.72) | CHRM2CHRM1CHRM4CHRM3USP2 | |
| SCHEMBL30741224 | 0.87 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3USP2 | |
| SCHEMBL6746859 | 0.87 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3USP2 | |
| SCHEMBL10935250 | 0.86 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL11078442 | 0.86 | CHRM2 (0.54) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL10932357 | 0.86 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL10932366 | 0.86 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL11084542 | 0.86 | CHRM2 (0.54) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL10931615 | 0.86 | CHRM2 (0.54) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085892-B1 | SUBSTITUTED BENZODIAZEPINONES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-12-18 | — | — | EP | disclosed |
| US-4447434-A | ANTIULCER, ANTISECRETORY, OR ANTICHOLINERGIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1984-05-08 | — | — | US | disclosed |
| EP-0085892-A1 | Substituted benzodiazepinones, process for their preparation and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1983-08-17 | — | — | EP | disclosed |