Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 11/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933216 | 0.95 | NPY5R (0.48) | NPY5RPOLBADRB2CYP3A4HTR1A | |
| SCHEMBL10931360 | 0.93 | NPY5R (0.49) | NPY5RKMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL10935015 | 0.93 | NPY5R (0.51) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL10937070 | 0.87 | POLB (0.36) | NPY5RPOLBADRB2CYP3A4HTR1A | |
| SCHEMBL10935069 | 0.85 | NPY5R (0.39) | NPY5RPOLBADRB2CYP3A4HTR1A | |
| SCHEMBL10933747 | 0.84 | NPY5R (0.37) | NPY5RPOLBADRB2CYP3A4HTR1A | |
| SCHEMBL10933929 | 0.83 | POLB (0.39) | NPY5RPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL10933516 | 0.82 | GRM4 (0.44) | NPY5RPOLBADRB2CYP3A4HTR1A | |
| SCHEMBL10932003 | 0.80 | ADORA1 (0.44) | NPY5RPOLBALDH1A1HPGDMAPT | |
| SCHEMBL11221756 | 0.80 | GRM4 (0.43) | NPY5RADRB2CYP3A4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042435-B1 | BENZOTHIAZINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-06-12 | — | — | EP | claimed |
| US-4358407-A | Benzothiazine derivatives | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1982-11-09 | — | — | US | claimed |
| US-4358407-A | Benzothiazine derivatives | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1982-11-09 | — | — | US | disclosed |
| EP-0042435-A1 | BENZOTHIAZINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-12-30 | — | — | EP | disclosed |