Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937070 | 0.89 | POLB (0.36) | NPY5RXIAPALOX5POLBHDAC3 | |
| SCHEMBL10933430 | 0.84 | NPY5R (0.45) | NPY5RALOX5POLBALDH1A1MAPT | |
| SCHEMBL10933516 | 0.84 | GRM4 (0.44) | NPY5RXIAPPOLBALDH1A1MAPT | |
| SCHEMBL10933216 | 0.83 | NPY5R (0.48) | NPY5RPOLBKMT2ATDP1ADRB2 | |
| SCHEMBL11221756 | 0.83 | GRM4 (0.43) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL10932003 | 0.82 | ADORA1 (0.44) | NPY5RPOLBALDH1A1MAPTHPGD | |
| SCHEMBL10935069 | 0.81 | NPY5R (0.39) | NPY5RALOX5POLBALDH1A1MAPT | |
| SCHEMBL10933929 | 0.81 | POLB (0.39) | NPY5RXIAPALOX5POLBALDH1A1 | |
| SCHEMBL10935015 | 0.81 | NPY5R (0.51) | NPY5RALDH1A1HPGDKMT2ATDP1 | |
| Bromide SCHEMBL11216358 | 0.81 | ADORA1 (0.43) | NPY5RPOLBALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042435-B1 | BENZOTHIAZINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-06-12 | — | — | EP | claimed |
| US-4358407-A | Benzothiazine derivatives | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1982-11-09 | — | — | US | claimed |
| EP-0042435-A1 | BENZOTHIAZINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-12-30 | — | — | EP | claimed |
| EP-0042435-B1 | BENZOTHIAZINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-06-12 | — | — | EP | disclosed |
| US-4358407-A | Benzothiazine derivatives | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1982-11-09 | — | — | US | disclosed |
| EP-0042435-A1 | BENZOTHIAZINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-12-30 | — | — | EP | disclosed |