Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132361 | 0.81 | PTGS2 (0.68) | MALT1PTGS1PTGS2LMNAMAOB | |
| SCHEMBL10932402 | 0.80 | MAOB (0.42) | SMN1; SMN2ALDH1A1LMNAMAOBMAOA | |
| SCHEMBL23410532 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2MALT1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL24747889 | 0.75 | PTGS1 (0.69) | SMN1; SMN2MALT1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL3353886 | 0.74 | PTGS2 (0.51) | PTGS1PTGS2 | |
| SCHEMBL3355870 | 0.72 | PTGS2 (0.55) | MALT1PTGS1PTGS2 | |
| SCHEMBL23410754 | 0.72 | MALT1 (0.50) | SMN1; SMN2MALT1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9489168 | 0.72 | SMN1; SMN2 (0.60) | SMN1; SMN2MALT1ALDH1A1LMNACYP1A2 | |
| SCHEMBL23420761 | 0.70 | SMN1; SMN2 (0.57) | SMN1; SMN2MALT1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL3355646 | 0.68 | PTGS2 (0.57) | PTGS1PTGS2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60233066-A | — | — | None | — | — | JP | disclosed |
| JP-S60233066-A | 1,5-DIPHENYLTRIAZOLE DERIVATIVE AND ITS PREPARATION | NIPPON NOHYAKU CO LTD | 1985-11-19 | — | — | JP | disclosed |