Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 10/20 | 0.51 |
| ▸ | PLG | P00747 | 8/20 | 0.51 |
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.51 |
| ▸ | KLK1 | P06870 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | C1R | P00736 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933691 | 1.00 | F12 (0.51) | F12PLGF2PRSS1KLK1 | |
| SCHEMBL10938260 | 0.94 | FTO (0.57) | F12PLGF2PRSS1KLK1 | |
| SCHEMBL8613432 | 0.80 | KMT2A (0.50) | ALDH1A1MAPT | |
| SCHEMBL8613434 | 0.80 | KMT2A (0.50) | ALDH1A1MAPT | |
| SCHEMBL7338981 | 0.78 | PLAU (0.63) | F12PLGF2PRSS1KLK1 | |
| SCHEMBL7338984 | 0.78 | PLAU (0.63) | F12PLGF2PRSS1KLK1 | |
| SCHEMBL10938112 | 0.78 | F12 (0.59) | F12PLGF2PRSS1KLK1 | |
| SCHEMBL10938267 | 0.78 | PLAU (0.41) | F12PLGF2PRSS1KLK1 | |
| SCHEMBL7347800 | 0.77 | PLAU (0.51) | F12PLGF2PRSS1KLK1 | |
| SCHEMBL7347803 | 0.77 | PLAU (0.51) | F12PLGF2PRSS1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496584-A | ANTITRYPSIN, ANTIKALLIKREIN, ANTITHROMBIN OR ANTIPLASMIN AGENT | TORII & CO. LTD. (JP) | 1985-01-29 | — | — | US | disclosed |