Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934704 | 0.88 | MEN1 (0.54) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10939304 | 0.81 | SLC2A1 (0.56) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10939250 | 0.78 | MEN1 (0.51) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL11012019 | 0.78 | MEN1 (0.52) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10934694 | 0.77 | MEN1 (0.47) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10941359 | 0.74 | KMT2A (0.48) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9416643 | 0.73 | KDM4E (0.81) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL7802750 | 0.72 | SLC2A1 (0.54) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL19194551 | 0.71 | KDM4E (0.59) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL3236287 | 0.71 | SLC2A1 (0.52) | MEN1KMT2AKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |