Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.81 |
| ▸ | BLM | P54132 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 4/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782844 | 0.87 | KDM4E (0.73) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28312736 | 0.86 | KDM4E (0.64) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9416658 | 0.83 | MEN1 (0.61) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2060386 | 0.82 | MAPK1 (0.63) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3232932 | 0.82 | MEN1 (0.64) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31388315 | 0.82 | MEN1 (0.64) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9416623 | 0.81 | HTT (0.61) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9416662 | 0.81 | HTT (0.61) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9416614 | 0.81 | LMNA (0.73) | KDM4EKMT2AMEN1NPC1RAB9A | |
| Bromide SCHEMBL20482559 | 0.81 | MAPK1 (0.61) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |