Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834390 | 0.88 | MEN1 (0.77) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL848495 | 0.87 | AKR1C3 (0.67) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL10939818 | 0.85 | MEN1 (0.60) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL10938004 | 0.85 | MEN1 (0.56) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL10834208 | 0.82 | MEN1 (0.54) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL10937794 | 0.82 | SIRT2 (0.61) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL9593627 | 0.80 | MEN1 (0.83) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL1026559 | 0.80 | ALDH1A1 (0.59) | MEN1LMNAKMT2AMAPTHPGD | |
| SCHEMBL10986815 | 0.79 | SMN1; SMN2 (0.54) | MEN1LMNAKMT2AMAPTPOLB | |
| SCHEMBL10934153 | 0.79 | AKR1C3 (0.57) | MEN1LMNAKMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539429-A | LIPOXYGENASE INHIBITORS, ANTIASTHMA | STERLING DRUG INC. (US) | 1985-09-03 | — | — | US | claimed |
| US-4539429-A | LIPOXYGENASE INHIBITORS, ANTIASTHMA | STERLING DRUG INC. (US) | 1985-09-03 | — | — | US | disclosed |
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0122518-A1 | Phenylaminobenzenealkanols and preparation | STERLING DRUG INC. (US) | 1984-10-24 | — | — | EP | disclosed |