Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 12/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884020 | 0.82 | ESR2 (0.57) | ESR2POLBESR1CYP3A4CYP2C9 | |
| SCHEMBL12045772 | 0.79 | ESR2 (0.45) | ESR2POLBESR1CYP3A4CYP2C9 | |
| SCHEMBL11588397 | 0.79 | ESR2 (0.55) | ESR2ESR1CYP3A4CYP2C9NR1H2 | |
| SCHEMBL18017090 | 0.74 | NOTUM (0.41) | NPC1RAB9A | |
| SCHEMBL31759479 | 0.74 | KDM4E (0.50) | ESR2POLBESR1CYP3A4CYP2C9 | |
| SCHEMBL24961822 | 0.73 | NPC1 (0.56) | ESR2POLBESR1CYP3A4CYP2C9 | |
| SCHEMBL5147779 | 0.73 | ESR2 (0.54) | ESR2POLBESR1CYP3A4CYP2C9 | |
| SCHEMBL13906346 | 0.72 | ESR2 (0.59) | ESR2POLBNPC1 | |
| SCHEMBL944630 | 0.72 | HTT (0.43) | ESR2RAB9AHRH3 | |
| SCHEMBL5146632 | 0.71 | ESR2 (0.52) | ESR2POLBESR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119615135-A | Electroless copper plating additive, electroless copper plating solution and electroless copper plating method for IC carrier plate | 深圳市板明科技股份有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-118970164-A | Three-dimensional crosslinked gel polymer electrolyte and preparation method and application thereof | 郑州比克电子有限责任公司 | 2024-11-15 | — | — | CN | claimed |
| CN-113122058-A | Preparation method of ink and quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-103965381-B | A kind of titanium tetrachloride initiator system altogether and the method being used for preparing high-activity polyisobutylene thereof | 北京化工大学 | 2016-08-24 | — | — | CN | claimed |
| CN-103965381-A | Titanium tetrachloride co-initiation system, and method for preparing high-reaction-activity polyisobutylene by using it | UNIV BEIJING CHEMICAL | 2014-08-06 | — | — | CN | claimed |
| CN-120058570-A | Application of metal ion doped graphene oxide film catalytic material in catalyzing thioether oxidation reaction to synthesize sulfone | 中国科学院理化技术研究所 | 2025-05-30 | — | — | CN | disclosed |
| CN-118970164-A | Three-dimensional crosslinked gel polymer electrolyte and preparation method and application thereof | 郑州比克电子有限责任公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-112533934-B | Polyoxometallate compounds exhibiting bright emissions and methods of making same | 纳米2D材料有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-113122058-A | Preparation method of ink and quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-112533934-A | Polyoxometallate compounds exhibiting bright emission and methods of making the same | 纳米2D材料有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-110256307-B | Method for synthesizing sulfoxide compound | 南京雷正医药科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-103736238-B | Fire extinguishing composition containing sulfur-containing organic compound | 湖北及安盾消防科技有限公司 | 2020-10-13 | — | — | CN | disclosed |
| EP-2281817-A1 | SUBSTITUTED CARBINOL COMPOUND HAVING CYCLIC LINKER | Kowa Company, Ltd. (JP) | 2011-02-09 | — | — | EP | disclosed |
| US-20100048610-A1 | CARBINOL DERIVATIVES HAVING CYCLIC LINKER | KOWA COMPANY, LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| CN-101490064-A | Novel glucokinase activators and methods of using same | BRISTOL MYERS SQUIBB CO (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-101395496-A | Use of bromine anions in an optical electrowetting device | VARIOPTIC SA (FR) | 2009-03-25 | — | — | CN | disclosed |
| US-6787651-B2 | 2-CARBOXY-SUBSTITUTED; TREATING OSTEOPENIA, OSTEOPOROSIS, CANCER, DIABETES AND ATHEROSCLEROSIS. | SMITHKLINE BEECHAM CORPORATION | 2004-09-07 | — | — | US | disclosed |
| EP-1341761-A1 | SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR-$g(g) BINDING AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-10 | — | — | EP | disclosed |
| US-20030087902-A1 | Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-gamma binding agents | SMITHKLINE BEECHAM CORPORATION | 2003-05-08 | — | — | US | disclosed |
| WO-2002030895-A1 | SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR-η BINDING AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087902-A1 | Substituted indoles, pharmaceutical compounds containing such indoles and their use as PPAR-gamma binding agents | PPARG, PPARA, PPARD | ESR2 120/4885POLB 2212/4885ESR1 397/4885 |
| US-20100048610-A1 | CARBINOL DERIVATIVES HAVING CYCLIC LINKER | NR1H2, NR1H3, LDLR | ESR2 614/4885POLB 1666/4885ESR1 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.