Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.56 |
| ▸ | OPRM1 known ✓ | P35372 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 5/20 | 0.56 |
| ▸ | HTR2A | P28223 | 7/20 | 0.55 |
| ▸ | HTR7 | P34969 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10936666 | 0.95 | MEN1 (0.67) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10935509 | 0.94 | MEN1 (0.68) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL10937634 | 0.85 | HRH3 (0.54) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10415232 | 0.84 | FAAH (0.63) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL11016070 | 0.84 | MAPK1 (0.67) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL10933082 | 0.83 | HRH3 (0.55) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| SCHEMBL10509762 | 0.83 | FAAH (0.52) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL11019890 | 0.83 | MAPK1 (0.68) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10507827 | 0.82 | DRD4 (0.53) | MAPK1FAAHCYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL10506832 | 0.82 | TP53 (0.62) | FAAHCYP3A4CYP2D6TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1985000811-A1 | NOVEL 1-PIPERAZINECARBOXAMIDE DERIVATIVES | AB FERROSAN (SE) | 1985-02-28 | — | — | WO | disclosed |