Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191191 | 0.94 | TDP1 (0.65) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL7642823 | 0.89 | HRH3 (0.61) | L3MBTL1KDM4EHRH3KMT2ACA12 | |
| SCHEMBL4085075 | 0.86 | CA12 (0.56) | TDP1L3MBTL1TP53KMT2ACA12 | |
| SCHEMBL465148 | 0.86 | KDM4E (0.65) | KDM4EHTTTP53TSHRPLA2G4B | |
| SCHEMBL10824877 | 0.86 | KDM4E (0.50) | TDP1L3MBTL1KDM4EHTTTP53 | |
| SCHEMBL17549737 | 0.84 | TDP1 (0.54) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL10080517 | 0.83 | HTT (0.55) | KDM4EHTTTP53TSHRPLA2G4B | |
| SCHEMBL6836190 | 0.83 | TP53 (0.71) | KDM4ETP53TSHRPLA2G4B | |
| SCHEMBL868230 | 0.83 | KMT2A (0.69) | KDM4ETP53TSHRPLA2G4BKMT2A | |
| SCHEMBL11852325 | 0.83 | TDP1 (0.67) | TDP1L3MBTL1HTTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60215648-A | — | — | None | — | — | JP | disclosed |
| JP-S60215648-A | 6,6'-(ETHYLENEDIOXY)-DI-2-NAPHTHOIC ACID, ITS DERIVATIVE AND PREPARATION THEREOF | TEIJIN LTD | 1985-10-29 | — | — | JP | disclosed |