SCHEMBL7642823

SCHEMBL7642823

CCOC(=O)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.61
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA7 P43166 3/20 0.59
CA9 Q16790 3/20 0.59
CA14 Q9ULX7 3/20 0.59
KDM4E B2RXH2 2/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
LMNA P02545 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAOA P21397 1/20 0.53
HSD17B2 P37059 1/20 0.53
ALDH1A1 P00352 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PTPN11 Q06124 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707407 0.93 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL10935339 0.89 TDP1 (0.59) HRH3CA12CA1CA2CA7
SCHEMBL9979785 0.89 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL1960994 0.87 CA12 (0.65) HRH3CA12CA1CA2CA7
SCHEMBL28292306 0.86 LMNA (0.59) HRH3KDM4EESR1LMNAALDH1A1
SCHEMBL29174292 0.86 HRH3 (0.52) HRH3CA12CA1CA2CA7
SCHEMBL571295 0.86 CA12 (0.59) HRH3CA12CA1CA2CA7
SCHEMBL30684671 0.86 CA12 (0.59) HRH3CA12CA1CA2CA7
SCHEMBL16259100 0.86 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL28117969 0.86 CA12 (0.59) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105324410-B Copolyesterimides derived from N, N ' -bis (hydroxyalkyl) -benzophenone-3, 3 ', 4,4 ' -tetracarboxylic diimide and films prepared therefrom 杜邦帝人薄膜美国有限公司 2017-03-22 CN disclosed
CN-105324411-B Derived from the copolyester imide of N, N ' double (hydroxy alkyl) 3,3 ', 4,4 ' double phenylsulfone tetracarboxylic imidodicarbonic diamide and the film that is produced from 杜邦帝人薄膜美国有限公司 2016-12-21 CN disclosed
EP-0755975-B1 A polyester composition and film TORAY INDUSTRIES (JP) 2002-03-20 EP disclosed
CN-1068642-C High strength core and sheath type filament for industrial use JOHNS MANVELLA INTERNAT CO (US) 2001-07-18 CN disclosed
CN-1068077-C High strength core and sheath type filament for industrial use JOHNSONS MANWILA INTERNAT CO (US) 2001-07-04 CN disclosed
CN-1146513-A Papermaking machine fabrics, filters and reinforcing layers for elastomers comprising monofilaments comprising specific copolyesters, stabilized copolyesters and use of copolyesters for manufactur.... HOECHST TREVIRA GMBH & CO KG (DE) 1997-04-02 CN disclosed
CN-1141359-A High strength core and sheath type filament for industrial use HOECHST TREVIRA GMBH & CO KG (DE) 1997-01-29 CN disclosed
CN-1141358-A High strength core and sheath type filament for industrial use HOECHST TREVIRA GMBH & CO KG (DE) 1997-01-29 CN disclosed